Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Msx1  msh homeobox 1   (Synonyms: Hox7, Hox-7, Hox7.1, msh, muscle-segment homeobox)
Results	Reference
1*	J:35170 Abud HE, Skinner JA, McDonald FJ, Bedford MT, Lonai P, Heath JK, Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge. Dev Genet. 1996;19(1):51-65
1	J:194074 Ahn Y, Sims C, Logue JM, Weatherbee SD, Krumlauf R, Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling. Development. 2013 Feb 1;140(3):583-93
1*	J:184022 Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R, Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech Dev. 2012 Mar;129(1-4):38-50
1	J:128020 Barbosa AC, Funato N, Chapman S, McKee MD, Richardson JA, Olson EN, Yanagisawa H, Hand transcription factors cooperatively regulate development of the distal midline mesenchyme. Dev Biol. 2007 Oct 1;310(1):154-68
1	J:181229 Bonilla-Claudio M, Wang J, Bai Y, Klysik E, Selever J, Martin JF, Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development. Development. 2012 Feb;139(4):709-19
1	J:153595 Butterfield NC, Metzis V, McGlinn E, Bruce SJ, Wainwright BJ, Wicking C, Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. Development. 2009 Oct;136(20):3515-24
1*	J:111160 Di Giacomo G, Koss M, Capellini TD, Brendolan A, Popperl H, Selleri L, Spatio-temporal expression of Pbx3 during mouse organogenesis. Gene Expr Patterns. 2006 Oct;6(7):747-757
1*	J:42445 Dunn NR, Winnier GE, Hargett LK, Schrick JJ, Fogo AB, Hogan BL, Haploinsufficient phenotypes in Bmp4 heterozygous null mice and modification by mutations in Gli3 and Alx4. Dev Biol. 1997 Aug 15;188(2):235-47
1*	J:54066 Dupe V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJA, Chambon P, Mark M, Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 1;208(1):30-43
1*	J:165424 Fuchs A, Inthal A, Herrmann D, Cheng S, Nakatomi M, Peters H, Neubuser A, Regulation of Tbx22 during facial and palatal development. Dev Dyn. 2010 Nov;239(11):2860-74
1	J:166947 Fujimori S, Novak H, Weissenbock M, Jussila M, Goncalves A, Zeller R, Galloway J, Thesleff I, Hartmann C, Wnt/beta-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 2010 Dec 1;348(1):97-106
1*	J:72150 Gong SG, Phenotypic and molecular analyses of A/WySn mice. Cleft Palate Craniofac J. 2001 Sep;38(5):486-91
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:78767 Guha U, Gomes W, Kobayashi T, Pestell R, Kessler J, In Vivo Evidence That BMP Signaling Is Necessary for Apoptosis in the Mouse Limb. Dev Biol. 2002 Sep 1;249(1):108
1	J:58673 Heymer J, Ruther U, Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression. Mech Dev. 1999 Nov;88(2):173-81
1	J:103321 Hilliard SA, Yu L, Gu S, Zhang Z, Chen YP, Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice. J Anat. 2005 Nov;207(5):655-67
1*	J:35171 Hofmann C, Luo G, Balling R, Karsenty G, Analysis of limb patterning in BMP-7-deficient mice. Dev Genet. 1996;19(1):43-50
1	J:173637 Horner VL, Caspary T, Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling. Dev Biol. 2011 Jul 1;355(1):43-54
1*	J:42035 Houzelstein D, Cohen A, Buckingham ME, Robert B, Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene. Mech Dev. 1997 Jul;65(1-2):123-33
1	J:187010 Jiang X, Zhou Y, Xian L, Chen W, Wu H, Gao X, The mutation in chd7 causes misexpression of bmp4 and developmental defects in telencephalic midline. Am J Pathol. 2012 Aug;181(2):626-41
1	J:194129 Lallemand Y, Moreau J, Cloment CS, Vives FL, Robert B, Generation and characterization of a tamoxifen inducible Msx1(CreERT2) knock-in allele. Genesis. 2013 Feb;51(2):110-9
1	J:184232 Lee K, Tan J, Morris MB, Rizzoti K, Hughes J, Cheah PS, Felquer F, Liu X, Piltz S, Lovell-Badge R, Thomas PQ, Congenital hydrocephalus and abnormal subcommissural organ development in Sox3 transgenic mice. PLoS One. 2012;7(1):e29041
1	J:102949 Li C, Xu X, Nelson DK, Williams T, Kuehn MR, Deng CX, FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis. Development. 2005 Nov;132(21):4755-64
1	J:118668 Li Q, Ding J, Gene expression analysis reveals that formation of the mouse anterior secondary palate involves recruitment of cells from the posterior side. Int J Dev Biol. 2007;51(2):167-72
1	J:97214 Liu W, Sun X, Braut A, Mishina Y, Behringer RR, Mina M, Martin JF, Distinct functions for Bmp signaling in lip and palate fusion in mice. Development. 2005 Mar;132(6):1453-61
1*	J:52212 Lu MF, Cheng HT, Lacy AR, Kern MJ, Argao EA, Potter SS, Olson EN, Martin JF, Paired-related homeobox genes cooperate in handplate and hindlimb zeugopod morphogenesis. Dev Biol. 1999 Jan 1;205(1):145-57
1*	J:39347 MacKenzie A, Purdie L, Davidson D, Collinson M, Hill RE, Two enhancer domains control early aspects of the complex expression pattern of Msx1. Mech Dev. 1997 Feb;62(1):29-40
1	J:334725 Markman S, Zada M, David E, Giladi A, Amit I, Zelzer E, A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation. Dev Cell. 2023 Apr 10;58(7):565-581.e4
1*	J:190997 Medio M, Yeh E, Popelut A, Babajko S, Berdal A, Helms JA, Wnt/beta-catenin signaling and Msx1 promote outgrowth of the maxillary prominences. Front Physiol. 2012;3:375
1*	J:83431 Morgan EA, Nguyen SB, Scott V, Stadler HS, Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia. Development. 2003 Jul;130(14):3095-109
1	J:262487 Murgai A, Altmeyer S, Wiegand S, Tylzanowski P, Stricker S, Cooperation of BMP and IHH signaling in interdigital cell fate determination. PLoS One. 2018;13(5):e0197535
1	J:219786 Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky A, Quaggin S, Vainio SJ, Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary. Exp Cell Res. 2015 Mar 15;332(2):163-78
1	J:135125 Pajni-Underwood S, Wilson CP, Elder C, Mishina Y, Lewandoski M, BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development. 2007 Jun;134(12):2359-68
1*	J:341657 Park J, Nakatomi M, Sasaguri M, Habu M, Takahashi O, Yoshiga D, Matsuyama K, Kataoka S, Toyono T, Seta Y, Peters H, Tominaga K, Msx1 Heterozygosity in Mice Enhances Susceptibility to Phenytoin-Induced Hypoxic Stress Causing Cleft Palate. Cleft Palate Craniofac J. 2021 Jun;58(6):697-706
1	J:332920 Shibuya S, Nakatomi M, Kometani-Gunjigake K, Nakao-Kuroishi K, Matsuyama K, Kataoka S, Toyono T, Seta Y, Kawamoto T, Msx1 is essential for proper rostral tip formation of the mouse mandible. Biochem Biophys Res Commun. 2023 Jan 29;642:75-82
1	J:57316 Sidow A, Bulotsky MS, Kerrebrock AW, Birren BW, Altshuler D, Jaenisch R, Johnson KR, Lander ES, A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant. Nat Genet. 1999 Sep;23(1):104-7
1	J:154460 Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aiba A, Kamijo R, Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development. Dev Biol. 2009 Nov 15;335(2):396-406
1*	J:33667 Takahashi Y, Organization of the spina bifida neural tube in Splotch (Pax-3 defective) mouse embryos. Dev Growth Differ. 1996 FEB;38(1):23-31
1	J:311534 Wan Y, Lantz B, Cusack BJ, Szabo-Rogers HL, Prickle1 regulates differentiation of frontal bone osteoblasts. Sci Rep. 2018 Dec 21;8(1):18021
1	J:264402 Welsh IC, Hart J, Brown JM, Hansen K, Rocha Marques M, Aho RJ, Grishina I, Hurtado R, Herzlinger D, Ferretti E, Garcia-Garcia MJ, Selleri L, Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. J Anat. 2018 Aug;233(2):222-242
1	J:154916 Welsh IC, O'Brien TP, Signaling integration in the rugae growth zone directs sequential SHH signaling center formation during the rostral outgrowth of the palate. Dev Biol. 2009 Dec 1;336(1):53-67
1*	J:182768 Wong YL, Behringer RR, Kwan KM, Smad1/Smad5 signaling in limb ectoderm functions redundantly and is required for interdigital programmed cell death. Dev Biol. 2012 Mar 1;363(1):247-57
1	J:56002 Xu X, Weinstein M, Li C, Deng C, Fibroblast growth factor receptors (FGFRs) and their roles in limb development. Cell Tissue Res. 1999 Apr;296(1):33-43
1*	J:54600 Zhang Y, Zhao X, Hu Y, St. Amand T, Zhang M, Ramamurthy R, Qiu M, Chen Y, Msx1 is required for the induction of Patched by Sonic hedgehog in the mammalian tooth germ. Dev Dyn. 1999 May;215(1):45-53
1	J:205040 Zhou J, Gao Y, Lan Y, Jia S, Jiang R, Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis. Development. 2013 Dec;140(23):4709-18
1	J:184918 Zhu X, Zhu H, Zhang L, Huang S, Cao J, Ma G, Feng G, He L, Yang Y, Guo X, Wls-mediated Wnts differentially regulate distal limb patterning and tissue morphogenesis. Dev Biol. 2012 May 15;365(2):328-38